Best Over The Counter Muscle Relaxer

Best Over The Counter Muscle Relaxer

Muscle relaxants and pain relievers are used to treat injuries and relieve pain. The FDA has approved two types of muscle relaxers: cyclobenzaprine (Flexeril) and methocarbamol or Robaxin). While they are effective, the side effects can be quite unpleasant. Muscle relaxers over the counter come in a topical form such as capsaicin, a topical cream applied to parts of the body that are experiencing pain caused by tense or contracted muscles.

Comparison Table

Top 8 Best Over The Counter Muscle Relaxer

1. Dee Cee Labs Formula 303 Maximum Strength All-Natural Relaxant Tablets

Dee Cee Labs Formula 303 Maximum Strength All-Natural Relaxant Tablets, 250 Tablets; All-Natural Relaxant containing Magnesium for Sore Muscles, Passion Flower, and Valerian Root

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Dee Cee Labs Formula 303 Maximum Strength All-Natural Relaxant Tablets, 250 Tablets Relax and ease muscle spasms and pain with Formula 303 Maximum Strength all-natural relaxant, made from natural ingredients. This herbal combination promotes better sleep, reduces stress and tension, helps lower blood pressure and more.

All-Natural Herbal Remedy

Formula 303 is an all-natural herbal remedy that harnesses the medicinal properties of valerian root, passionflower, and magnesium to provide you with relaxed muscles, stress relief, and natural relief from muscle pain relief, joint pain relief, leg cramp relief, and stress relief.

Perfectly Formulated

The best for muscle relief, stress and sleep imbalance. For Full Spectrum, support uses the combination of Formula 303 Relax & Sleep with the natural Magnesium supplement Formulation 310.

Natural Ingredients

Formula 303 is made from natural ingredients and may have a distinctive earthy odor, the taste, and color of tablets may vary.

Made In USA

Gluten-Free, Non-GMO manufactured for almost 60 years in the USA, in an FDA registered and inspected facility in full compliance with current Good Manufacturing Processes.

2. Amazon Basic Care Naproxen Sodium Tablets

Amazon Basic Care Naproxen Sodium Tablets, 300 Count

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Amazon Basic Care Naproxen Sodium Tablets, 300 Count is a 220 mg nonsteroidal anti-inflammatory drug (NSAID) that relieves minor aches and pains due to minor pain of arthritis, muscular aches, backache, menstrual cramps, headache, toothache, and the common cold. This all-day pain reliever can be taken every 12 hours for up to 5 days. Amazon Basic Care Naproxen Sodium Tablets are gluten-free.

Active Ingredient

This pain reliever and fever reducer contain naproxen sodium 220 mg, a nonsteroidal anti-inflammatory drug (NSAID); compare to the active ingredient in Aleve Caplets.

Aches And Pains

Temporarily relieves minor aches and pains due to minor pain of arthritis, muscular aches, backache, menstrual cramps, headache, toothache and the common cold; also temporarily reduces fever.

All-Day Relief

Amazon Basic Care Naproxen Sodium Tablets 220 mg is a pain reliever and fever reducer for adults and children aged 12 years and over.

Capsule-Shaped Tablets

This 12-hour pain reliever and fever reducer come in a capsule-shaped tablet; this product is gluten-free.

3. SaltWrap Mag R&R – Nighttime Muscle Cramps

SaltWrap Mag R&R - Nighttime Muscle Cramps & Relaxation Support, Relaxing Natural Sleep Support for Adults with Magnesium Glycinate for Muscle Spasm and Leg Cramps Relief, 90 Capsules

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SaltWrap Mag R&R is an all-natural solution to the cause of night muscle cramps, leg spasms, and discomfort. This nighttime support works with your body’s own natural chemistry to promote relaxation and sleep so you wake up ready for the day ahead. The powerful synergy of magnesium glycinate, 5-HTP, and melatonin will help you relax tense muscles and optimize your sleep cycle without leaving you groggy in the morning.

Muscle Cramp And Spasm Relief

Mag R&R leg cramp pills contain highly bioavailable Magnesium Glycinate to help support healthy muscle and nerve function. Unlike cheaper forms such as oxide or chloride (which can cause stomach distress), magnesium glycinate is thought to be absorbed by intestinal walls without causing stomach discomfort.

Clinically Supported Formulation

With a blend of clinically supported minerals and herbs, Mag R&R may help you relieve muscle tension while inducing feelings of calmness. The natural nutrients in this formula work to support healthy sleep patterns for those who occasionally deal with leg cramps at night.

Eight Muscle Relaxing Ingredients

These cramp relief capsules contain precise dosages of 8 relaxing ingredients including Magnesium Bisglycinate, Passion Flower, and super-herbs like Rhodiola and Ashwagandha that may help boost endurance, mental performance, and support healthy stress levels.

Relaxing Sleep Support

Our magnesium sleep support supplement blend also contains a combination of 5-HTP and GABA. When combined, these two amino acids have a synergetic effect that may help support sleep.

Quality You Can Count On

Proudly MADE IN USA (in GMP Approved Facility) with Premium Ingredients. Mag R & R comes with a 100% GUARANTEE – If you don’t love it after one dose, simply contact us and we’ll refund your money. No questions asked.

4. Aleve Back & Muscle Pain Relief Naproxen Sodium Tablets

Aleve Back & Muscle Pain Relief Naproxen Sodium Tablets ‐ 250 Count, 250 Count

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Aleve Back & Muscle Pain Relief is an effective, all-day pain reliever that provides targeted relief of minor aches and pains. These tablets are fast-acting, so they start working quickly to provide targeted relief of back and muscle aches.

Each tablet has the strength to last up to 12 hours for long-lasting pain relief. It’s easy to use, just take one pill every 4–6 hours as needed or as directed by your doctor. Plus, each pack comes with child‐resistant packaging so you can keep it in reach without worrying about curious little hands getting into it.

How Does Work

Aleve Back & Muscle Pain contains 220mg of active ingredient naproxen sodium in each pill. It works by temporarily blocking the body’s production of naturally occurring chemicals called prostaglandins, resulting in a reduced pain signal to the brain.

Back & Muscle Pain

Back and muscle pain can be caused by poor posture, prolonged sitting, lifting improperly, heavy backpacks, muscle sprains or strains, injury or trauma.

Knee Pain

Your knees are among the most important joints in your body. Knees support your weight and provide stability.

Shoulder Pain

Your shoulders are among the most important joints in your body. Shoulders are the most moveable, but also the most unstable joints in the body, as they are highly dependent on the surrounding muscles and ligaments to hold them in place.

5. Zenium Anti-Stress & Anxiousness Relief Supplement

Zenium Anxious Feelings Relief & Stress Support Supplement | Calm The Mind & The Body | Boosts Mood | Happy Pills | All Natural | Valerian, Ashwagandha, L-Theanine, GABA, 5HTP, Rhodiola | 60 Capsules

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Zenium is a plant-based, all-natural supplement designed to help calm the mind and body, reduce stress and anxiousness, improve sleep and increase focus. The combination of 5HTP, GABA, Valerian Root, and Ashwagandha can be especially beneficial for those suffering from sleep disorders such as insomnia.

Struggling With Anxious Feelings & Tension In The Body?

Stress & anxiousness can be paralyzing and debilitating. Take control of your thoughts. Relax the tension in your body with our plant-based, all-natural supplement that really works.

We Know The Feeling

Backed by research studies, Zenium’s plant-based, the vegan formula was beta-tested and perfected over several years by a homeopath who suffered from high levels of stress and anxiousness.

Worry Less & Sleep More

Start the day off feeling rested, full of energy & with a positive outlook. Triggers can throw you into a dark place. Silence and calm your mind with Zenium.

9+ Powerful Ingredients

Zenium Tranquility includes Ashwagandha, 5-HTP, L-Theanine, GABA, Magnesium, Rhodiola Rosea, Lemon Balm, Valerian Root, Gotu Kola, and many other adaptogens.

30 Day Satisfaction Guarantee

If you are on the fence about trying Zenium, don’t be. We want you to be totally confident. If you do not feel like Zenium works for you let us know, and we will issue a full refund. No questions asked.

6. Relaxeril™ Best All-Natural Muscle Relaxer

Relaxeril™ All-Natural Muscle Relaxer - Complete Formula for Lasting Leg Cramp, Soreness, Back Spasm, and Tension Relief - Muscle Relaxer Supplement to Ease Pain and Promote Deep Sleep

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Relaxeril™ is the most effective, all-natural muscle relaxer on the market. Relaxer provides long-lasting pain and cramps relief without the dangers of pills or chemicals. Our natural ingredients are derived from Mother Nature and have been shown in clinical studies to be highly effective at helping you relax, sleep deeper, prevent soreness and back spasms and ease cramps.

Safe and Effective

The high-potency formula contains precise concentrations of clinically-proven natural muscle relaxers for faster, long-lasting relief. It’s not uncommon to experience reduced soreness, less cramping, and deep rejuvenating sleep in just a matter of days. All in the SAFEST ALL-NATURAL WAY.

Naturally, Fight the Root Causes of Soreness and Tension

Fight the root causes of your pain with the only formula on the market made of ingredients shown to support healthy bones and muscles. Targeted support for muscle contraction and bones means you could experience a DRASTIC LONG-TERM REDUCTION IN SORENESS OR CRAMPS naturally.

Optimize Sleep. Wake Up Refreshed

Stop letting stiff muscles and back cramps ruin your sleep. The optimal mixture of natural sedatives and muscle cramp protection in our relaxant means you fall asleep faster, stay asleep longer, and wake up feeling refreshed and energetic.

The Only Complete All-Natural Formula

100% Money-Back Guarantee: This is the only supplement that contains our unique formula developed to completely support relief through relaxation, pain relief, and long-term support so you can avoid the negative effects of painkillers. We are firmly dedicated to our values of honesty, transparency, and purity. So we only use ingredients that have shown to work in scientific studies and on our own bodies.

7. WishGarden Herbs Serious Relaxer

WishGarden Herbs Serious Relaxer - All Natural Muscle Relaxation Supplement, Muscle Recovery, Soothes Muscle Tension, Muscular-Skeletal Discomforts and Inflammation, with Wild Lettuce Extract (4oz)

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Serious Relaxer & Muscle Tension tincture is an organic herbal supplement made with wild lettuce extract, kava and valerian root that can relax and support a tense or tired body. No matter if you’re a mom after a long day of parenting or an athlete after a hard day of training, these natural herbs are the first step to calming down after a stressful day. Hit the reset button and start to relax with our gluten-free, non-GMO natural muscle soothers.

Supports Your Tense Or Tired Body

Organic herbal formula quickly eases the body into a relaxed and calm state. Eases muscle tension and soreness, soothes achy joints and muscular-skeletal discomforts and repetitive motion strain.

Liquid Form That Absorbs Quickly

Liquids are quickly and easily absorbed by the body. They allow you to customize your serving to best meet your needs, they are easy to swallow, and they are convenient for on-the-go use.

Certified Organic & Wild-harvested Ingredients

Our staff of highly trained herbalists uses only quality-tested gluten-free and non-GMO ingredients to produce our signature formulations that soothe, nurture and support our bodies in the way nature intended.

Commitment To Sustainability

We make remedies from a love of plants and the earth, so sustainability is very important to us. Each of our suppliers goes through an extensive screening process and must meet our high standards for sustainability & quality.

Radically Effective Remedies Since 1979

We are herbalists, botanists, scientists and naturalists making herbal formulas the old-fashioned way. WishGarden is woman-owned and family-run in Colorado.

8. SaltWrap Mag 3D – Daytime (Non-Drowsy) Muscle Relax Pills

SaltWrap Mag 3D – Daytime (Non-Drowsy) Muscle Relax Pills for Leg Cramps Relief & Muscle Spasms, Natural Supplement for Nerve Health, Aches & Pains with Turmeric, Alpha Lipoic Acid & Magnesium

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Mag 3D is the only non-drowsy natural muscle relaxer on the market. This unique formula addresses all three root causes of muscle spasms, cramps, pain and tension: Magnesium deficiency leading to high levels of calcium ions in your nervous system’s cells, leading to increased nerve irritability that sets off painful muscle contractions; low blood circulation that puts strain on muscles; and mineral deficiencies (copper and potassium), affecting energy production and nutrient transport in your body.

Non-drowsy Relief From Muscle Spasms And Cramps

Mag 3D contains non-drowsy natural ingredients that actually boost energy levels by improving circulation, nerve health, and muscular function (cramp and pain relief without grogginess). Mag 3D is the only non-drowsy natural muscle relaxer on the market.

Three Ways Mag 3d Relieves Spasms, Cramps, Aches & Pains

  • Supports total nerve health.
  • Improves nutrient & blood circulation.
  • Prevents mineral deficiencies that lead to muscular & nerve dysfunction.

Addresses All Three Root Causes

ADDRESSES ALL THREE ROOT CAUSES of muscle spasms, cramps, pain and tension. Unlike other supplements or OTC products that address only symptoms, Mag 3D gets to the root of your cramps and pain.

Clinically-supported Natural Ingredients

Made in the USA in a GMP Approved Facility with clinically-supported, trademarked ingredients including Albion Magnesium, Curcumin C3 Complex Turmeric Extract, and BioPerine Black Pepper Extract.

Saltwrap’s Quality Guarantee

Mag 3D is 100% GUARANTEED. If you don’t love it after one dose, we’ll refund your money. No questions asked (the seller of this item, SaltWrap, is solely responsible for all guarantees stated). We encourage you to use Mag 3D for a full 30 days to get the full benefit. But, you are welcome to request a refund anytime within 90 days of your purchase by contacting us directly.

What Is The Best Muscle Relaxer?

Best Over The Counter Muscle Relaxer

Because each category of muscle relaxant has its own set of advantages and applications, it is difficult to determine which is best. Pain relief treatments can be divided into three main categories: OTC, prescription, and natural remedies. Muscle relaxers should only be chosen based on your personal situation and level of discomfort. It’s best to consult with your doctor if you’re unsure about an issue.

Over The Counter Remedies

When it comes to treating pain, inflammation, and tension, over-the-counter pain relievers are often the first port of call. Milder conditions like neck and lower back pain can be effectively treated with them. If an over-the-counter (OTC) medication doesn’t provide the necessary relief, your primary care physician will most likely prescribe medication of higher quality, such as a prescription.

Prescription Drugs

A more powerful medication may be prescribed to you by your doctor if you have more severe pain or a condition for which over-the-counter medications have not been helpful. Prescription muscle relaxants are only meant to be used for short periods of time due to the more serious side effects they can cause. Your doctor will most likely switch you to another medication or treatment after this time period.

Natural Remedies

Natural remedies may be all you need to alleviate your symptoms, whether they are stress-related or minor aches and pains. A plant-based therapy can be both effective and convenient, so you don’t need to rush to the doctor for an examination and possible prescription.


I think you’ll find that topical muscle relaxants are likely the most effective over-the-counter relaxers for muscle cramps. I also included a link to the oral medication cyclobenzaprine, which is FDA approved for tension headaches and can be used as a relaxer for mild muscle aches and some types of pain. It will likely not be as strong as something like Flexeril or Rugulin, but if high doses are needed, Flexeril and Rugulin are prescription-only drugs.






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